Pannier Lab
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Pannier Lab Group

Pannier Lab Group Fall 2017

The long-term goal of the Pannier Lab is to understand and design innovative biomaterials and gene delivery systems to advance biotechnology, diagnostics, fundamental understanding of embryology and tissue development, and regenerative medicine therapies. Research projects within the Pannier Lab are focused in three different themes including nonviral gene delivery, tissue engineering, and protein-cell-biomaterial interactions.

Within the nonviral gene delivery theme, our aim is to determine and understand the mechanisms that render cells responsive to the transfer of genetic material (e.g. DNA), concentrating on the cell microenvironment, the interaction between cells and biomaterials, and the intracellular processes and subsequent signaling involved during nonviral gene delivery. Within the tissue engineering theme, our objective is to develop biomaterial scaffolds and culture systems to understand and promote tissue, organ, and organism development, regeneration, and growth. Within the protein-cell-material interaction theme, projects aim to make use of a novel combinatorial spectroscopic ellipsometry and quartz crystal microbalance with dissipation analytical technique to uncover new and unique information on processes that occur at biomaterial interfaces, which are critical to the performance of biomaterials in biotechnological and therapeutic applications.

The experimental approaches developed in the Pannier Lab provide valuable insights to the fields of gene delivery and biomaterials, with very promising potential for future scientific discovery and translation to therapeutic, biotechnological, and tissue engineering applications.


Dr. Pannier's NSF CAREER Award Highlights




Andrew Hamann graduated in May 2017 with M.S. degree.

Freshta Baher and Austin Helmink (with honors) graduated in May 2017 with B.S. degree in Biological Systems Engineering.

Bailey Eddy, Matthew Boren and Connor States were awarded UCARE undergraduate fellowships.

Dr. Pannier was awarded the UNL-Wide Outstanding Undergraduate Research Mentor Award, the Darrell W. Nelson Outstanding Graduate Advisor Award, and the College of Engineering Tau Beta Pi Distinguished Teaching Award.

Amy Mantz and Dr. Pannier for their visiting scholar positions at Leibniz-Institut für Polymerforschung, Dresden e. V., Germany for Summer 2017!

The Pannier Lab for being awarded a 2017 USDA NIFA Grant for our project on tissue engineering for pig embryos!



Erickson, Alek G., Laughlin Taylor D., Romereim Sarah M., Sargus-Patino Catherine N., Pannier Angela K., and Dudley Andrew T. Tissue Engineering
Part A. May 2017, ahead of print.

Laughlin TD, Miles JR, Wright-Johnson EC, Rempel LA, Lents CA, Pannier AK.
Reproductive Fertil Dev. 2017.

Miles JR, Laughlin TD, Sargus-Patino CN, Pannier AK. 2017. In vitro porcine blastocyst development in three-dimensional alginate hydrogels. Mol Reprod Dev. 9999:1–13.