Pannier Lab
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Pannier Lab Group

Pannier Lab Group Fall 2016

The long-term goal of the Pannier Lab is to understand and design innovative biomaterials and gene delivery systems to advance biotechnology, diagnostics, fundamental understanding of embryology and tissue development, and regenerative medicine therapies. Research projects within the Pannier Lab are focused in three different themes including nonviral gene delivery, tissue engineering, and protein-cell-biomaterial interactions.

Within the nonviral gene delivery theme, our aim is to determine and understand the mechanisms that render cells responsive to the transfer of genetic material (e.g. DNA), concentrating on the cell microenvironment, the interaction between cells and biomaterials, and the intracellular processes and subsequent signaling involved during nonviral gene delivery. Within the tissue engineering theme, our objective is to develop biomaterial scaffolds and culture systems to understand and promote tissue, organ, and organism development, regeneration, and growth. Within the protein-cell-material interaction theme, projects aim to make use of a novel combinatorial spectroscopic ellipsometry and quartz crystal microbalance with dissipation analytical technique to uncover new and unique information on processes that occur at biomaterial interfaces, which are critical to the performance of biomaterials in biotechnological and therapeutic applications.

The experimental approaches developed in the Pannier Lab provide valuable insights to the fields of gene delivery and biomaterials, with very promising potential for future scientific discovery and translation to therapeutic, biotechnological, and tissue engineering applications.


Dr. Pannier's NSF CAREER Award Highlights




Amy Mantz graduated with an M.S. degree in August 2016.

Taylor Laughlin graduated in August 2016 with a M.S. degree.

Christopher Davidson awarded NSF and graduated in May 2016 with B.S. degree in Biological Systems Engineering.

Albert Nguyen graduated in December 2015 with a M.S. degree.

Sarah Plautz received the IANR Outstanding Employee Award (2015 4th quarter).

Austin Helmink and Jordan Verplank were awarded UCARE.

Eric Farris won 1st place in Graduate Student Poster Fair.


Kasputis T, Pieper A, Rodenhausen KB, Schmidt D, Sekora D, Rice C, Franke-Schubert E, Schubert M, Pannier AK. 2015. Use of precisely-sculptured thin film (STF) substrates with generalized ellipsometry to determine spatial distribution of adsorbed fibronectin to nanostructured columnar topographies and effect on cell adhesion. Acta Biomater. 18:88-99.

Martin TM, Wysocki BJ, Wysocki TA, Pannier AK.  2015. Identifying intracellular pDNA losses from a model of nonviral gene delivery. IEEE Trans Nanobioscience. Epub ahead of print.

Martin TM, Plautz SA, Pannier AK. 2015. Temporal endogenous gene expression profiles in response to lipid-mediated transfection. J Gene Med. 17(1-2):14-32.

Martin TM, Plautz SA, Pannier AK. 2015. Temporal endogenous gene expression profiles in response to polymer-mediated transfection and profile comparison to lipid-mediated transfection. J Gene Med. 17(1-2):33-53.